CHLAMYDIA

Chlamydia infection is caused by the organism Chlamydia trachomatis. It is the most common sexually-transmitted disease in the United States. Sexually active individuals and individuals with multiple partners are at highest risk. Chlamydia may be acquired jointly with gonorrhea and/or syphilis so individuals with one sexually transmitted disease must be screened for other sexually transmitted diseases as well. Untreated chylamidia can lead to pelvic infection and infertility.

In men, chlamydia may produce symptoms similar to those of gonorrhea (discharge from penis or rectum, burning on urination or defecation), and can also cause epididymitis and orchitis. However, up to 25% of infected men may have no symptoms.

Chlamydia (female): only approximately 30% of women will have symptoms due to chlamydia -- hence screening sexually active women for chlamydia is necessary to diagnose and treat asymptomatic women in order to decrease the risk of developing complications. Women who do have symptoms may note vaginal discharge, burning on urination, or abdominal pain. Untreated infection may lead to pelvic inflammatory disease (PID) which can cause scarring of the Fallopian tubes and result in infertility. Tubal scarring also increases the likelihood of an ectopic pregnancy (tubal pregnancy). If a women is infected with chlamydia while pregnant, the infection can cause premature labor and delivery. In addition, the infant may develop chlamydial conjunctivitis (eye infection) and chlamydial pneumonia.

Prevention

Safe sexual practices and consistent condom use are important prevention measures to help decrease infection with chlamydia. In addition, sexually active individuals (in particular women with new or multiple sexual partners) should be periodically screened for chlamydia.

Symptoms

MALE

burning sensation during urination

discharge from the penis

testicular tenderness or pain

rectal discharge or pain


FEMALE

vaginal discharge

burning sensation during urination

sexual intercourse, painful

symptoms of PID, salpingitis, perihepatitis (liver inflammation similar to hepatitis)

rectal pain or discharge

Signs and tests

The diagnosis of chlamydia infection involves sampling of the urethral discharge in males or cervical secretions in females. If an individual engages in anal sexual contact, samples from the rectum may also be needed. The sample is sent for a fluorescent or monoclonal antibody test, DNA probe test or cell culture. Some of these tests may also be performed on urine samples.

Treatment

The mainstay of therapy for chlamydia includes appropriate antibiotic treatment -- these include: tetracyclines, azithromycin or erythromycin. All sexual contacts should be screened for chlamydia. Sexual partners must be treated to prevent passing the infection back and forth. There is no significant immunity following the infection and a person may become repeatedly infected.

A follow-up evaluation may be done in 4 weeks to determine if the infection has been cured.

Prognosis

Early antibiotic treatment is extremely successful and may prevent the development of long-term complications. Untreated infection, however, may lead to PID , scarring and ultimately infertility.

Complications

pelvic inflammatory disease (PID)

salpingitis

infertility

ectopic pregnancy



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