Solpaflex tablets FactFile

 

 

How does it work?
This medicine contains two active ingredients, ibuprofen and codeine phosphate. Both are pain-relieving medicines.
Ibuprofen is a type of medicine called a non-steroidal anti-inflammatory drug (NSAID). It relieves pain and inflammation. Ibuprofen works by blocking the action of a substance in the body called cyclo-oxygenase.
Codeine phosphate is a type of painkiller called an opioid. It is related to morphine but is not as strong. Opioid painkillers work by mimicking the action of naturally occurring pain-reducing chemicals called endorphins. Endorphins are found in the brain and spinal cord and reduce pain by combining with opioid receptors.
Codeine phosphate mimicks the action of natural endorphins by combining with the opioid receptors in the brain and spinal cord. This blocks the transmission of pain signals sent by the nerves to the brain. Therefore, even though the cause of the pain may remain, less pain is actually felt.
This combination of painkillers can be used to relieve pain and inflammation associated with various conditions. These include rheumatic, arthritic and muscular aches and pains, sprains and strains, period pains, headache and migraine, backache, dental pain and neuralgia.

 

What is it used for?

 

n Abdominal pain associated with dysmenorrhea

n Pain and inflammation

n Pain relief in migraines

n Painful inflammatory disorders affecting the muscles, bones and joints, eg back pain, tendon inflammation (tendinitis)

n Rheumatic aches and pains

n Severe throbbing or stabbing pain along a nerve and in the area supplied by the nerve (neuralgia)

n Sprains, strains and sport injuries

n Toothache

n should have their kidney function monitored.

 

Side effects

Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.

n Headache

n Abdominal pain

n Constipation

n Drowsiness

n Nausea

n Indigestion (dyspepsia)

n Ulceration of the stomach or intestine

n Dizziness

n Bleeding from the stomach or intestine

n Hypersensitivity reactions such as narrowing of the airways (bronchospasm), swelling of the lips, throat and tongue (angioedema), itchy blistering rash or anaphylactic shock

n Kidney disorders

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